% This LaTex template is for manuscripts to be included in
% ISCA conference proceedings.
%
\documentclass[letterpaper,twocolumn]{article}
%
\usepackage[raggedright]{titlesec}
%
% include packages as needed, such as
%\usepackage{amsmath}
%\usepackage{amsthm}
\usepackage{graphicx}
\usepackage{float}
%\usepackage[ruled,vlined]{algorithm2e}
%\usepackage{array}
%\usepackage{multirow}
\usepackage{url}
%\usepackage{subfigure}
%etc.

\graphicspath{ {pictures/} }

%no page numbers
\pagestyle{empty}

\setlength{\textwidth}{7.0in}
\setlength{\textheight}{9.125in}
\setlength{\columnsep}{0.375in}
%\setlength{\topmargin}{-0.8in}
\setlength{\oddsidemargin}{-0.25in}
\setlength{\evensidemargin}{-0.25in}
\setlength{\parindent}{0.125in}
\setlength{\parskip}{1mm}

\renewcommand\labelenumi{(\theenumi)}

\date{}

\titlespacing{\section}{0pt}{*2.0}{*2.0}
\titlespacing{\subsection}{0pt}{*1.8}{*1.8}

\renewcommand{\topfraction}{0.9}
\renewcommand{\textfraction}{0.1}

\hyphenpenalty=5000
\tolerance=1000

\begin{document}
\bibliographystyle{plain}

\date{}
\title{\Large\bf ModFossa: A Python Library for Ion Channel Modeling}
\author{\begin{tabular}[t]{c@{\extracolsep{6em}}c}
Gareth Ferneyhough &   Corey Thibeault      \\
Sergiu M. Dascalu  &  Frederick C. Harris, Jr.  \\
                  \end{tabular} 
									\\ \\
Computer Science and Engineering \\						
University of Nevada, Reno    \\
Reno, NV, USA   \\   
}
\maketitle
\thispagestyle{empty}


\subsection*{\centering Abstract}


The creation and simulation of ion channel models using continuous-time Markov
processes is a powerful and well-used tool in the field of electrophysiology
and ion channel research. While several software packages exist for the purpose
of ion channel modeling, none are available as a Python library. In an attempt
to provide an easy-to-use, yet powerful Markov model-based ion channel
simulator, we have developed ModFossa, a Python library supporting easy model
creation and stimulus definition, complete with a fast numerical solver, and
attractive vector graphics plotting. \\
\medskip
\noindent
\textbf{keywords:} Neuroscience, Simulation, ModFossa

\section{Introduction\label{sec:Intro}} 
\input{Sec-01-Intro.tex}

\section{Background\label{sec:Background}}
\input{Sec-02-Background.tex}

\section{Design Overview\label{sec:Design}}
\input{Sec-03-Design.tex}

\section{Results\label{sec:Results}}
\input{Sec-04-Results.tex}

\section{Discussion and Future Work\label{sec:Conclusion}}
\input{Sec-05-Concl-Future.tex}


%\bibliographystyle{abbrv}
%\bibliography{Sec-07-References}

\itemsep=0pt
\bibliography{bibliography}

\end{document} 
